BDBM50587894 CHEMBL5187375

SMILES Cc1nn(-c2ccc(F)cc2)c2c(Nc3ccc(F)c(Cl)c3)ncnc12

InChI Key InChIKey=LBSCIFOFCMWXSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587894   

TargetEpidermal growth factor receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50587894(CHEMBL5187375)
Affinity DataIC50: 180nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 30 min in presence of ATP by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50587894(CHEMBL5187375)
Affinity DataIC50: 250nMAssay Description:Inhibition of ErbB2 (unknown origin) pre-incubated for 5 mins followed by substrate addition and measured after 30 mins in presence of ATP by microti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed