BDBM50587913 CHEMBL5174387

SMILES COc1ccc(\C=C\C(=O)c2cc(ccc2O)-n2cc(CN3C(=O)C(=O)c4ccccc34)nn2)cc1

InChI Key InChIKey=JKGWGMHMKRQONI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50587913   

TargetProstaglandin G/H synthase 2(Human)
National Forensic Sciences University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587913BDBM50587913(CHEMBL5174387)
Affinity DataIC50: 37nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Forensic Sciences University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587913BDBM50587913(CHEMBL5174387)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Forensic Sciences University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587913BDBM50587913(CHEMBL5174387)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
National Forensic Sciences University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587913BDBM50587913(CHEMBL5174387)
Affinity DataIC50: 7.40E+3nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed