BDBM50587919 CHEMBL5173810

SMILES CNc1cc(F)cc2c1[nH]c1nc(Oc3cnc(C)nc3)nc(N3CC\C(C3)=C(/F)CN)c21

InChI Key InChIKey=WUKWZMALCNEIIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587919   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50587919(CHEMBL5173810)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of hERG potassium channel assessed as maximum inhibition rate at -80 mV holding potential incubated for 120 seconds by whole cell-automate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed