BDBM50587988 CHEMBL5172754

SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3cccc4ccccc34)cc2c1=O

InChI Key InChIKey=SWFYRRCYIDSQGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50587988   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50587988(CHEMBL5172754)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of recombinant His-tagged wild-type HIV-1 group M subtype B BH10 reverse transcriptase-associated RNase H activity harboring p66/p51 hetro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universita di Roma

Curated by ChEMBL
LigandPNGBDBM50587988(CHEMBL5172754)
Affinity DataIC50: 4.19E+4nMAssay Description:Inhibition of HIV-1 integrase catalytic activity incubated for 1 hrs in absence of LEDGF/p75 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universita di Roma

Curated by ChEMBL
LigandPNGBDBM50587988(CHEMBL5172754)
Affinity DataEC50: >2.00E+5nMAssay Description:Inhibition of HIV1 integrase activity by measuring multimerization of His-tagged integrase/FLAG-tagged integrase incubated for 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed