BDBM50588045 CHEMBL5206309

SMILES O=C1[C@H](Nc2cc(F)cc(Cl)c2)CCCN1[C@@H]1CCCN(c2ncnc3[nH]ncc23)C1

InChI Key InChIKey=COXQUJPRGLQAKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588045   

TargetTyrosine-protein kinase BTK(Human)
Biogen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50588045BDBM50588045(CHEMBL5206309)
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK (unknown origin) incubated 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEarly activation antigen CD69(Human)
Biogen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50588045BDBM50588045(CHEMBL5206309)
Affinity DataIC50: 90nMAssay Description:Inhibition of CD69 (unknown origin) in PBMC preincubated for 30 mins followed by IL-4 stimulation for 3 days by cell titer glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed