BDBM50588261 CHEMBL5170524
SMILES COc1cc(ccc1-c1ccnc2[nH]c(cc12)C1CCNCC1)C(=O)N1CCCC1
InChI Key InChIKey=VBWQPLLCGUWXEE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50588261
Affinity DataIC50: <3nMAssay Description:Inhibition of CDK9 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK1 (unknown origin) using 5FAM-RRRFRPASPLRGPPK-COOH as substrate preincubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CDK2 (unknown origin) using FL-Ahx-QSPKKG-CONH2 as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK9 in human MCF7 cells assessed as reduction in RNA polymerase II phosphorylation at ser2 residue incubated for 6 hrs by fluorescence...More data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of CDK12 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK12 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of full length human GSK3beta in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK1 (unknown origin) using 5FAM-RRRFRPASPLRGPPK-COOH as substrate preincubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin) using FL-Ahx-QSPKKG-CONH2 as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CDK7 (unknown origin) using 5FAM-YSPTSPSYSPTSPSYSPTSPSKKKK-NH2 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CDK7 (unknown origin) using 5FAM-YSPTSPSYSPTSPSYSPTSPSKKKK-NH2 as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair