BDBM50588513 CHEMBL5176872

SMILES COc1ccc(CN2CCN(CC2)C(=O)c2cc3ccc(Oc4cnc(cn4)-c4nc(no4)-c4ccc(cc4)C(F)(F)F)cc3n2C)cc1F

InChI Key InChIKey=ACZSZIAQWYCMQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50588513   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50588513(CHEMBL5176872)
Affinity DataIC50:  134nMAssay Description:Inhibition of STAT3 in human HEK293T cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed