BDBM50588559 CHEMBL5203176

SMILES CCC(=O)N1CCC(CC1)Oc1nc(Nc2ccc(cc2)N2CCN(C)CC2)nc2ccsc12

InChI Key InChIKey=VJFWYGXUQZBYSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588559   

TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588559(CHEMBL5203176)
Affinity DataIC50: 268nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant wild type EGFR (695 to end residues) expressed in baculovirus-infected Sf9 cells using poly (4:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588559(CHEMBL5203176)
Affinity DataIC50: 356nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant EGFR T790M/L858R mutant (695 to end residues) expressed in baculovirus-infected Sf9 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed