BDBM50589183 CHEMBL5180158

SMILES CC(C)[C@H]1Cc2cc(ccc2S(=O)(=O)N(C1)C[C@H]([C@H](Cc3ccccc3)NC(=O)O[C@H]4CCOC4)O)F

InChI Key InChIKey=NTBLOIDJWKXDON-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589183   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM50589183(CHEMBL5180158)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to HIV-1 protease assessed as inhibition constant incubated for 60 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM50589183(CHEMBL5180158)
Affinity DataKi:  360nMAssay Description:Inhibition of HIV-1 protease using Val-Ser-Gln-Asn-(beta-naphthylalanine)-Pro-Ile-Val as substrate preincubated with enzyme followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed