BDBM50589643 CHEMBL5197933

SMILES COc1ccc(cc1OC)-c1noc(n1)-c1cc(Cl)ccc1-n1cncn1

InChI Key InChIKey=OSVORJSIGHIQJK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50589643   

TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589643(CHEMBL5197933)
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589643(CHEMBL5197933)
Affinity DataIC50: 1.10E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589643(CHEMBL5197933)
Affinity DataIC50: 6.30E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50589643(CHEMBL5197933)
Affinity DataIC50: 6.31E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed