BDBM50589770 CHEMBL5188502

SMILES Clc1ccc(cc1Cl)N1CCN(C[C@H]1C(=O)NCc1cccs1)C(=O)c1cncc2ccccc12

InChI Key InChIKey=RINFEVYWSYRNHT-DEOSSOPVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50589770   

TargetCaspase-3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589770(CHEMBL5188502)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human caspase-3 using Ac-Asp-Glu-Val-Asp-pNA as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetReplicase polyprotein 1ab(2019-nCoV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589770(CHEMBL5188502)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetCathepsin B(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589770(CHEMBL5188502)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human Cathepsin B using Z-Leu-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetCathepsin F(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589770(CHEMBL5188502)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human Cathepsin F using Z-Phe-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetCathepsin K(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589770(CHEMBL5188502)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human Cathepsin K using Ac-LR-AMC as fluorogenic substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetProcathepsin L(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50589770(CHEMBL5188502)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human Cathepsin L using Z-Leu-Arg-AMC as fluorogenic substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed