BDBM50590111 CHEMBL5200248

SMILES O=C(Nc1nc(-c2ccc(F)cc2F)cs1)[C@@H]1[C@H](C(=O)O)[C@@H]2C=C[C@H]1C2

InChI Key InChIKey=BWLIWSKMFJDEAA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590111   

Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
UT Southwestern Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590111BDBM50590111(CHEMBL6078430)
Affinity DataIC50: 470nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
UT Southwestern Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590111BDBM50590111(CHEMBL6078430)
Affinity DataIC50: 580nMAssay Description:Agonist activity at mouse PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
UT Southwestern Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590111BDBM50590111(CHEMBL6078430)
Affinity DataIC50: 1.60E+3nMAssay Description:Agonist activity at mouse PPARdelta assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed