BDBM50590378 CHEMBL5200425

SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1cccc2n([C@H](C)C3CCOCC3)c(C)cc12

InChI Key InChIKey=YMYDGZPZCSJMJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50590378   

TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590378(CHEMBL5200425)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using monomethylated H3K27 as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed