BDBM50590682 CHEMBL5192545

SMILES CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc3c(NC(=O)CN(C)C)n[nH]c3c2)ncc1Cl

InChI Key InChIKey=FFMOPKLRQAOMEL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50590682   

TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed