BDBM50590685 CHEMBL5180262

SMILES CCN(CC)CC(=O)Nc1n[nH]c2cc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)ccc12

InChI Key InChIKey=FYGLIPNJRSHMFG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50590685   

TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed