BDBM50590834 CHEMBL5176561

SMILES CCC(=O)NNC(=O)c1csc2ncc(-c3ccc(C)cc3)n12

InChI Key InChIKey=VNEUERRAUAGHGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590834   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50590834(CHEMBL5176561)
Affinity DataIC50: 244nMAssay Description:Inhibition of recombinant human HER2 incubated for 40 to 45 mins and measured after 15 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50590834(CHEMBL5176561)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human EGFR incubated for 40 to 45 mins and measured after 15 mins by Kinase-Glo Max assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50590834(CHEMBL5176561)
Affinity DataIC50: 5.67E+3nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli incubated for 15 mins and measured by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed