BDBM50590939 CHEMBL5174830

SMILES CN(C)CC#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1

InChI Key InChIKey=DORZPJWJOBMQKC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50590939   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590939BDBM50590939(CHEMBL5174830)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590939BDBM50590939(CHEMBL5174830)
Affinity DataIC50: 4nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590939BDBM50590939(CHEMBL5174830)
Affinity DataIC50: 4nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590939BDBM50590939(CHEMBL5174830)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590939BDBM50590939(CHEMBL5174830)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMyosin light chain kinase, smooth muscle(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590939BDBM50590939(CHEMBL5174830)
Affinity DataIC50: 265nMAssay Description:Inhibition of MYLK in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590939BDBM50590939(CHEMBL5174830)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAP4K5 in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed