BDBM50591142 CHEMBL5209405::US20240034730, Compound 30

SMILES CC(C)c1cc(NC(=O)c2c(O)nn3ccccc23)c(C)cc1Oc1ccccc1

InChI Key InChIKey=HLAPQJIQMWVQKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591142   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591142(CHEMBL5209405 | US20240034730, Compound 30)
Affinity DataIC50: 114nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591142(CHEMBL5209405 | US20240034730, Compound 30)
Affinity DataIC50: 114nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed