BDBM50591322 CHEMBL5196686

SMILES CN1CC[C@H](C1)Oc1ccc(Cl)c(c1)-c1nc2c(o1)C(=O)c1ccccc1C2=O

InChI Key InChIKey=CBCIEAZGJGQSMW-CYBMUJFWSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50591322   

TargetUbiquitin thioesterase OTUB1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of N-terminal His-6 tagged OTUB1 (40 to 271 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Ub-Rho measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of N-terminal His-6 tagged USP8 (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells measured after 3 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of USP1 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtaxin-3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ataxin-3 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 36(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of USP36 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed