BDBM50591542 CHEMBL5173787

SMILES Cc1ccc2N(C(=O)C3CCCCC3)C(=O)C3(SCC(=O)N3CCCC(O)=O)c2c1

InChI Key InChIKey=RXXKUWFUMWWTHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591542   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591542BDBM50591542(CHEMBL5173787)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed