BDBM50591545 CHEMBL5184604

SMILES [H][C@@]12CS[C@@]([H])([C@H](CC(C)C)NC(=O)OCc3ccccc3)N1C(=O)N(CCCNCCCN)C2=O

InChI Key InChIKey=JQJHURSEYIQCRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591545   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Federico Ii of Naples

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591545BDBM50591545(CHEMBL5184604)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed