BDBM50591632 CHEMBL5184593

SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(Cc2ccc(cc2)C(=O)Nc2ccccc2N)ccc1OCC

InChI Key InChIKey=IUKGCTNFPZAWGC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50591632   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 114nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 114nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 114nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 673nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 673nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591632(CHEMBL5184593)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed