BDBM50592039 CHEMBL5179538

SMILES COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC(=O)NCCNc2cccc3C(=O)N(Cc23)C2CCC(=O)NC2=O)CC1

InChI Key InChIKey=ZZEWLUKGFOHQPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50592039   

TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592039(CHEMBL5179538)
Affinity DataIC50: 965nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 35 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50592039(CHEMBL5179538)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed