BDBM50592346 CHEMBL5190773
SMILES [H][C@@]12COP(S)(=O)O[C@@]3([H])[C@@H](O)[C@@H](O[C@]3([H])COP(S)(=O)O[C@]([H])([C@@H]1O)[C@@H](O2)n1cnc2c(N)ncnc12)n1cnc2c(N)ncnc12
InChI Key InChIKey=IZJJFUQKKZFVLH-UHFFFAOYSA-N
Data 5 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50592346
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 131nMAssay Description:Agonist activity at STING in PMA-treated human THP-1 reporter cells incubated for 30 mins in presence of digitonin by QUANTI-Luc assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 154nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 4 hrs in presence of lipofectamine 2000 by QUANTI-Luc assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.01E+3nMAssay Description:Agonist activity at STING R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by wash...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.92E+3nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 24 hrs by QUANTI-Luc assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.32E+3nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells measured after 7 hrs by Bright-glo luciferase assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 2.42E+4nMAssay Description:Agonist activity at wild type STING (unknown origin) expressed in HEK293T cells preincubated for 30 mins followed by washout and measured after 6.5 h...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 4.15E+4nMAssay Description:Agonist activity at STING in human THP-1 cells by IFN-reporter based assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 4.15E+4nMAssay Description:Agonist activity at STING (unknown origin)More data for this Ligand-Target Pair