BDBM50592351 CHEMBL5188508

SMILES CCn1nc(C)cc1C(=O)Nc1nc2cc(sc2n1C\C=C\Cn1c(NC(=O)c2cc(C)nn2CC)nc2cc(cc(OC(C)C)c12)C(N)=O)C(N)=O

InChI Key InChIKey=CBXSLZYODXAFNV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50592351   

TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592351(CHEMBL5188508)
Affinity DataEC50:  5.82E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592351(CHEMBL5188508)
Affinity DataEC50:  6.37E+4nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed