BDBM50593047 CHEMBL5172448

SMILES CC(C)(C)NC(=O)c1ccnc(c1)C#Cc1ccc2c3c(oc2c1)C(C)(C)c1cc(NS(C)(=O)=O)ccc1C3=O

InChI Key InChIKey=RFCPQXPQIFCVHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50593047   

TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593047(CHEMBL5172448)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593047(CHEMBL5172448)
Affinity DataIC50: 130nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593047(CHEMBL5172448)
Affinity DataIC50: 600nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed