BDBM50593081 CHEMBL5204489

SMILES CC(C)c1cccc(NC(=O)CCc2cccc(c2)-c2cnc3[nH]ccc3c2)c1

InChI Key InChIKey=ONYCJILVRZEEQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593081   

TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593081(CHEMBL5204489)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed