BDBM50593220 CHEMBL5207152

SMILES F[C@@H]1Cc2c(ncn2C1)C(C(=O)Nc1nccs1)n1cc2c(Cl)cc(-c3ccc(cc3)N3CCN(CC3)C3CC3)c(Cl)c2n1

InChI Key InChIKey=MINSHXJSQFGWCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593220   

TargetEpidermal growth factor receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50593220(CHEMBL5207152)
Affinity DataIC50: 17nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50593220(CHEMBL5207152)
Affinity DataIC50: 30nMAssay Description:Inhibition of EGFR L858R/C797S mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed