BDBM50593305 CHEMBL5186181

SMILES Cc1cnc(Nc2ccc(cc2)S(C)(=O)=O)nc1Nc1ccc2oc(=O)[nH]c2c1

InChI Key InChIKey=UTHSJMMRZFAMFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593305   

TargetJAK3/JAK1(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50593305(CHEMBL5186181)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed