BDBM50593704 CHEMBL5186874
SMILES CN1CCC(CC1)n1cc(Nc2nc(NC3(C)CC3)c3c(ccn(CC(F)F)c3=O)n2)cn1
InChI Key InChIKey=GHVMKCWQHYDLSH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50593704
Affinity DataIC50: 83nMAssay Description:Inhibition of IRAK4 in IL1-stimulated human KARPAS-299 cells assessed as fluorescence intensityMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant IRAK4 assessed as unphosphorylated KKARFSRFAGSSPSQSSMVAR peptide substrate measured after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair