BDBM50594016 CHEMBL5204083

SMILES OC(=O)c1cc(ccc1O)-c1ccc(CNc2ccc(cc2)C(=O)c2ccc(NC(=O)CCCC#C)cc2)o1

InChI Key InChIKey=WRVKONWQUFWQKF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50594016   

TargetL-lactate dehydrogenase B chain(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594016(CHEMBL5204083)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant LDHB using pyruvate as substrate preincubated for 10 mins followed by substrate addition and measured every 60 sec fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594016(CHEMBL5204083)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant LDHA using pyruvate as substrate preincubated for 10 mins followed by substrate addition and measured every 60 sec fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target2-Hydroxyacid oxidase 1(Mouse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594016(CHEMBL5204083)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target2-Hydroxyacid oxidase 1(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594016(CHEMBL5204083)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594016(CHEMBL5204083)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate measured every 60 sec for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed