BDBM50594115 CHEMBL5172110

SMILES [H][C@@]1(CC[C@@H](CC1)N(C)C)[C@]1(C)Oc2c(O1)c(Cl)c1CCN(Cc3c(SC)cc(C)[nH]c3=O)C(=O)c1c2C

InChI Key InChIKey=JBITZLMCDYBANM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594115   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594115(CHEMBL5172110)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Affiliated Hospital of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594115(CHEMBL5172110)
Affinity DataKi:  63nMAssay Description:Binding affinity to EZH2 (unknown origin) expressed in baculovirus infected Sf9 cells using H3K27me1 (H2N-RKQLATKAAR Kme1)SAPATGGVKKP-NTPEGBiot) as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed