BDBM50594347 CHEMBL5189303

SMILES [H][C@]12C[C@H](N(c3nc(N)nc(N)c3C#N)[C@@]1([H])CCCC2)c1nc2cccc(F)c2c(=O)n1-c1cccnc1

InChI Key InChIKey=DUEZCIIABAXAPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594347   

LigandPNGBDBM50594347(CHEMBL5189303)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kdelta expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594347(CHEMBL5189303)
Affinity DataIC50: 3.64E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594347(CHEMBL5189303)
Affinity DataIC50: 1.55E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kbeta expressed in baculovirus infected Sf21 insect cells incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594347(CHEMBL5189303)
Affinity DataIC50: 3.12E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kalpha expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed