BDBM50594724 CHEMBL5193247

SMILES CN(C)CC(=O)NCCOc1cc2NCN=C(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C

InChI Key InChIKey=RMZISWVBRKVMOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594724   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594724(CHEMBL5193247)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594724(CHEMBL5193247)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594724(CHEMBL5193247)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594724(CHEMBL5193247)
Affinity DataIC50:  103nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed