BDBM50594827 CHEMBL5171745

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O

InChI Key InChIKey=OKFCZQOQWOKJMP-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594827   

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594827(CHEMBL5171745)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]DAMGO from human MOP expressed in CHO-K1 cell membrane incubated for 60 mins by Microscint-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594827(CHEMBL5171745)
Affinity DataEC50:  0.940nMAssay Description:Agonist activity at human MOP expressed in CHO-K1 cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594827(CHEMBL5171745)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]U69593 from human KOP expressed in CHO-K1 cell membrane incubated for 60 mins by Microscint-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594827(CHEMBL5171745)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]DPDPE from human DOP expressed in CHO-K1 cell membrane incubated for 60 mins by Microscint-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed