BDBM50595396 CHEMBL5196864

SMILES [H][C@@]12CN(Cc3cccc(c3)C#N)C[C@@]([H])(C1)c1c(ccc(=O)n1C2)-c1ccc2ccccc2c1

InChI Key InChIKey=DRTMJXOVPWKHSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50595396   

TargetSerine/threonine-protein kinase PLK1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595396(CHEMBL5196864)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of 5-carboxyfluoresceinGPMQSpTPLNG-OH peptide binding to human PLK1 (326 to 603 residues) PBD expressed in Rosetta BL21 (DE3) cells preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed