BDBM50595405 CHEMBL5184598

SMILES O[C@@H](CNCCCCOC(=O)c1ccc(COc2cccc(c2)[C@H](NC(=O)O[C@H]2CN3CCC2CC3)c2ccccc2)cc1)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=GTJTVOBMGAUNFW-AQVMEVBTSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50595405   

TargetBeta-2 adrenergic receptor(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50595405(CHEMBL5184598)
Affinity DataKi:  0.0501nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50595405(CHEMBL5184598)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBeta-2 adrenergic receptor(Guinea pig)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50595405(CHEMBL5184598)
Affinity DataIC50:  0.501nMAssay Description:Invivo agonist beta2 adrenoceptor activity in Dunkin-Hartley guinea pig trachea assessed as histamine induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor(Guinea pig)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50595405(CHEMBL5184598)
Affinity DataIC50:  7.90nMAssay Description:Invivo antagonist activity at muscarinic M3 receptor activity in Dunkin-Hartley guinea pig trachea assessed as inhibition of carbachol induced contra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed