BDBM50595876 CHEMBL5209116::US20240336629, Compound 2

SMILES C[C@@H](COCCC(=O)N1CCN2C(C1)C(=O)Nc1cc(cnc21)C(F)(F)F)Nc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=BAYLVRHCVANSLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50595876   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50595876(CHEMBL5209116 | US20240336629, Compound 2)
Affinity DataIC50: 0.584nMAssay Description:Inhibition of PARP7 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50595876(CHEMBL5209116 | US20240336629, Compound 2)
Affinity DataIC50: 0.584nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandPNGBDBM50595876(CHEMBL5209116 | US20240336629, Compound 2)
Affinity DataIC50: 27nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) Tuner cells assessed as dec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50595876(CHEMBL5209116 | US20240336629, Compound 2)
Affinity DataIC50: 31nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) Tuner cells assessed as dec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed