BDBM50596218 CHEMBL5195236

SMILES Nc1ncc(-c2cnn(CC3CCCNC3)c2)c2CCN(C3CCCCC3)C(=O)c12

InChI Key InChIKey=JDYMCSKANXEKMK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50596218   

TargetActivin receptor type-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50596218(CHEMBL5195236)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50596218(CHEMBL5195236)
Affinity DataIC50: 42nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50596218(CHEMBL5195236)
Affinity DataIC50: 267nMAssay Description:Inhibition of ALK2 in human HeLa cells assessed as inhibition of SMAD1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50596218(CHEMBL5195236)
Affinity DataIC50: 274nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed