BDBM50596244 CHEMBL5208596

SMILES COc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@]1(C)CS(=O)(=O)[C@@](C)(CF)C(=N)N1

InChI Key InChIKey=DDJPZDFVKYYYNV-OALUTQOASA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596244   

TargetBeta-secretase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50596244(CHEMBL5208596)
Affinity DataKi:  5nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50596244(CHEMBL5208596)
Affinity DataIC50:  1.47E+4nMAssay Description:Displacement of MK499 from human ERG expressed in HEK membrane by radio ligand binding competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50596244(CHEMBL5208596)
Affinity DataIC50:  12nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293 cells expressing human APP with Swedish and London familial AD mutationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed