BDBM50596254 CHEMBL5198665
SMILES Cc1cc(cnc1C(=O)Nc1ccc(F)c(n1)[C@]1(C)CS(=O)(=O)[C@@](C)(C(F)F)C(=N)N1)C#N
InChI Key InChIKey=IWBMTMOXRFICLO-PMACEKPBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50596254
Affinity DataKi: 1nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.89E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: >1.91E+4nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
Affinity DataKi: >3.06E+4nMAssay Description:Inhibition of human cathepsin EMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human ERG expressed in HEK cells by voltage clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.82E+4nMAssay Description:Displacement of MK499 from human ERG expressed in HEK membrane by radio ligand binding competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of NaV1.2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.06E+3nMAssay Description:Inhibition of CAV1.2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293 cells expressing human APP with Swedish and London familial AD mutationMore data for this Ligand-Target Pair