BDBM50596396 CHEMBL5201174

SMILES CCc1nc(C(N)=O)c(Cc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1CN1CCOCC1

InChI Key InChIKey=LFADPAKTJDMCEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596396   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50596396(CHEMBL5201174)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50596396(CHEMBL5201174)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of FLT3-D835Y autophosphorylation in human MV4-11 cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50596396(CHEMBL5201174)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FLT3-ITD autophosphorylation in human MV4-11 cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed