BDBM50596720 CHEMBL5200635::US12527775, Compound I-014

SMILES CC(C)COc1ccc(CNC(=O)N(Cc2ncc(F)cc2F)C2CCN(C)CC2)cc1

InChI Key InChIKey=CXDAWYJEMGTVJX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596720   

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50596720BDBM50596720(CHEMBL5200635 | US12527775, Compound I-014)
Affinity DataKi: <10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details Article
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50596720BDBM50596720(CHEMBL5200635 | US12527775, Compound I-014)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50596720BDBM50596720(CHEMBL5200635 | US12527775, Compound I-014)
Affinity DataKi:  55nMAssay Description:In advance, 0.5 μL of the compound solution dissolved in DMSO was dispensed into a microplate, and the cell membrane and the hot ligand were diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details Article
US Patent