BDBM50597448 CHEMBL5180195
SMILES CCO\N=C1\c2ccccc2-c2nc(C#N)c(nc12)C#N
InChI Key InChIKey=VKVAJBRQGBRHIK-ZHZULCJRSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50597448
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair