BDBM50597470 CHEMBL5207169

SMILES COc1cccc(c1)[C@@H](C)NC(=O)c1ccc(cn1)-c1ccnc(F)c1

InChI Key InChIKey=SXONWTYLDXUYAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50597470   

TargetRho-associated protein kinase 2(Human)
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50597470(CHEMBL5207169)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human ROCK2 (5 to 554 residues) expressed in baculovirus infected Sf9 cells using S6K as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed