BDBM50597569 CHEMBL5179476

SMILES Cc1cc(=O)n(c(C)n1)-c1ccc(N2CCC(Cc3ccc(Cl)c(F)c3)CC2)c(Cl)c1

InChI Key InChIKey=QJJAWWTXNFNKHS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50597569   

TargetCytochrome P450 1A2(Human)
Hec Pharma.

Curated by ChEMBL
LigandPNGBDBM50597569(CHEMBL5179476)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Hec Pharma.

Curated by ChEMBL
LigandPNGBDBM50597569(CHEMBL5179476)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Hec Pharma.

Curated by ChEMBL
LigandPNGBDBM50597569(CHEMBL5179476)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Hec Pharma.

Curated by ChEMBL
LigandPNGBDBM50597569(CHEMBL5179476)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Hec Pharma.

Curated by ChEMBL
LigandPNGBDBM50597569(CHEMBL5179476)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597569(CHEMBL5179476)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG stably expressed in CHO cells by automated Qpatch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed