BDBM50597649 CHEMBL4277262

SMILES Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(O)=O)C=O)C=O

InChI Key InChIKey=NVPIJHRHNNQNDN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597649   

LigandPNGBDBM50597649(CHEMBL4277262)
Affinity DataKi:  950nMAssay Description:Inhibition of recombinant human NPP3 expressed in HEK293 cells using p-Nph-5'-TMP as substrate measured after 60 mins by mini-capillary electrophores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597649(CHEMBL4277262)
Affinity DataKi:  5.14E+3nMAssay Description:Inhibition of recombinant human ENPP1 using ATP as substrate assessed as inhibition constant incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597649(CHEMBL4277262)
Affinity DataKi:  5.62E+3nMAssay Description:Binding affinity to ENPP1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed