BDBM50597836 CHEMBL5186778

SMILES CC(C)Oc1ccc(F)c(c1)-c1cnc(N)c(n1)C(=O)Nc1cnccc1N1CCCC(C1)C(O)=O

InChI Key InChIKey=UZIATSFXNVOVFE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50597836   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50:  6nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50:  6nMAssay Description:Inhibition of human wild type DYRK1A (M1 to S629) expressed in bacterial system by Ambit Kinomescan binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50:  40nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50:  6nMAssay Description:Inhibition of human DYRK1A at 3 uM in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed