BDBM50598014 CHEMBL2179350

SMILES OC(=O)c1cc(O)c2cc(NC(=O)Nc3ccc4cc(cc(O)c4c3)C(O)=O)ccc2c1

InChI Key InChIKey=SIWVJBJPYHPOMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50598014   

TargetProtein arginine N-methyltransferase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50598014(CHEMBL2179350)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human PRMT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50598014(CHEMBL2179350)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of recombinant human PRMT1 assessed as residual activity using biotinylated histone H4 (1 to 21) as substrate incubated for 60 mins in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50598014(CHEMBL2179350)
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of recombinant C-terminal GST-tagged PRMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50598014(CHEMBL2179350)
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of GST-tagged human PRMT1 expressed in Escherichia coli BL21 cells using Npl3p as substrate preincubated with substrate for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed