BDBM50598640 CHEMBL5203850

SMILES Cc1ccc(NC(=O)C(=C\c2ccc(o2)-c2ccc(cc2)C(O)=O)\C#N)cc1C

InChI Key InChIKey=MTORWNWKELZKSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50598640   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50598640(CHEMBL5203850)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of human recombinant SIRT5 using fluorogenic Benzyl-Lys(Succinyl)-AMC as substrate incubated for 2 hrs measured by fluoroscence based micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed